International Case Reports Journal (ISSN: 2770-9647) | Volume 2, Issue 4 | Case Report | Open Access

Soft Tissue Rhabdoid Tumour in a 19 Year Old African Male: A Case Report

Thulo Molefi*

1Department of Medical Oncology, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa

2Department of Anatomical Pathology, National Health Laboratory Services, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa

*Correspondence to: Thulo Molefi 

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Abstract

Rhabdoid Tumours (RT) is rare, rapidly progressive neoplasms that typically occur in childhood; are often metastatic at presentation and are known for their high mortality. These malignancies are even rarer in adults, occur at a variety of anatomic locations and are classified into three categories. A 19 year old male with no pre-existing illnesses or family history of malignancy, presented with metastatic malignant extrarenal, extracranial rhabdoid tumour (MERT) and after a short period of investigation and therapy demised within a year of his diagnosis. A definitive chemotherapy regimen is yet to be identified for this malignancy and despite the identification of a candidate drug target; the management of rhabdoid tumours remains a therapeutic challenge. Further study is required to underpin the molecular biology of this malignancy and with better understanding, targeted therapy will be discovered and applied; particularly for irresectable and metastatic disease.

Keywords:

MERT, Rhabdoid Tumour, SMARCB1

Citation:

Thulo Molefi, Christa Solomon. Soft Tissue Rhabdoid Tumour in a 19 Year Old African Male: A Case Report. Int Case Rep Jour. 2022;2(4):1-5.