Archives of Chronic Diseases | Volume 1, Issue 1 | Research Article | Open Access

A Retrospective Study on Beneficial Effects of Alprostin in Patients with Critical Limb Ischemia and Peripheral Arterial Disease

Fenil Gandhi*

1 Head of Department, Vascular Surgery, Shree Krishna Hospital 2 MBBS, Vascular Surgery, Shree Krishna Hospital 3 Research Project Associate, Memorial Sloan Kettering Cancer Center, New York, USA

*Correspondence to: Fenil Gandhi 

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Abstract

Medical management of non re-constructible and failed reconstruction in patients with Peripheral Arterial Disease (PAD) has limited options. The objective was to study the safety and efficacy of Alprostin in the management of the patients presenting with Stages III and IV PAD. We hypothesized that administration of Alprostin will lead to an increase in the TcPO2 and ABI values. It may also aid in decreasing limb pain, promote ulcer healing and increase claudication distance.

Keywords:

Peripheral arterial disease; Alprostadil; Leg ulcer; Ischemia

Citation:

Gandhi F, Patel J, Shah P. A Retrospective Study on Beneficial Effects of Alprostin in Patients with Critical Limb Ischemia and Peripheral Arterial Disease. Arch of Chron Disea Jour. 2021;1(1):1-7.